III    D.   How an Enzyme catalyzed reaction takes place
                        -- ANSWERS

               (You may be also go to Video Disk [HRW 2975,  2981 (3 Fr.)] or transparency)

                The pictures have been removed to save space.

            1.   an enzyme (protein) is a chain of many   A M I N O      A C I D S                                 

            2.   the catalytic part of the enzyme (a protein) is known as its  A C T I V E    S I T E     

3.   the  A C T I V E    S I T E   and the   S U B S T R A T E   must temporarily join

            4.   This joining is called the  E N Z Y M E  -  S U B S T R A T E  (E-S) 
           C O M P L E X

            5.   The E-S complex then   S E P A R A T E S

            6.   The enzyme (yellow in the above model) of course is  U N C H A N G E D, while the
          substrate is   C H A N G E D

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