Name _______________________ Date ________ Period ___

Translation Animation Script to accompany http://www.ncc.gmu.edu/dna/ANIMPROT.htm

1. Initiation (of the process of T _ _ _ _ _ A _ _ _ N) occurs when the …
a. mRNA (the long strand showing 21 rectangular _ N A _ I _ R _ _ _ _ BASES comprised
of _______ (a number) different colors representing bases of G, C, A & __),

b. the small ribosomal subunit (medium grey oval), and

c. the large ribosomal subunit (dark grey ¾ of an almost circle) along with

d. the methionine (one of 20 ________ ______ in your diet (shown as a bright red oval)) -

2. The next tRNA (its symbolic color is ______) carrying …
a. its amino acid (its symbolic color is dark ____) arrives at
b. the A site (ignore this site designation until the next step) and

c. peptidase (from its spelling, peptidase must be a(n) __________) causes the formation of

d. a peptide bond (same root as _ _PEPTIDE and _ _ _ _PEPTIDE) between the 2 amino acids.

3. The enzyme translocase (trans means A _ _ O _ _ and loc is short for LOC _ _ _ _ _) moves …

1. down the growing peptide (made from ________ ______ subunits) chain to the
2. tRNA at the A (short for amino acid assembly) site, and the
3. tRNA at the P (growing protein) site leaves.
4. The _ _ B _ _ O M _ (not the mRNA) slides down one codon (a group of _____ nitrogen

   bases),

5. and the (former) A(SSEMBLY) site becomes the (new) P(ROTEIN) site as a new A site
   is created.

4. The process of elongation (this refers to the length of the AMINO ACID CHAIN) repeats until …

a. a termination code (Examine Pelican Text p. 192, Fig. 10.8A) is reached at the A site.
There are only _____ (a number) known termination codes. Different authors refer to
them as either "Stop" or "None" on codon charts such as this one.

b. Each mRNA codon consists of _____ (a number) of RNA nucleotides with code
contained in the differences in their ___________ _______.

c. The first of these mRNA bases in the codon is displayed on the far left of Fig. 10.8A.

d. The second of these mRNA bases in the codon is displayed on the top of Fig. 10.8A.

e. The third of these mRNA bases in the codon is displayed on the far right of Fig. 10.8A.

f. The three stop codons are U A _, _ _ _ and _ _ _

g. The initiation or start codon for the same amino acid (1 d above) is A U G which codes
for the amino acid (3 letter code) Met which is short for ________________.

h. In fact all the three letter codes within Fig. 10.8A are short for different _______ ______.

i. If the amino acid is leucine, then the 3 letter code (on Fig. 10.8A) is _ _ _

j. If the amino acid is arginine, then the 3 letter code (on Fig. 10.8A) is _ _ _ (Don’t argue)

k. If the amino acid is alanine, then the 3 letter code (on Fig. 10.8A) is _ _ _ (Hint Birmingham)

l. This (refers to any of the three S _ _ _ codons) signals the end of translation (of this particular
gene), but the very next three nitrogen bases are often _ _ G which then INITIATES
decoding of a new gene

5. All the components disassemble (move _ P _ _ _ ) as the protein has been made.